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Thread: A Cheering Development

  1. #1
    Ardross
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    Last Updated: Friday, 24 September, 2004, 11:21 GMT 12:21 UK

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    Baby for ovary transplant woman


    Tamara is the first baby to be born to a woman after an ovary transplant
    A cancer patient made infertile by chemotherapy has, in a world first, given birth after revolutionary treatment, Belgian doctors say.
    Ovarian tissue from the Belgian mother, 32, was removed and frozen seven years ago before chemotherapy, then re-implanted into her pelvis last year.

    She conceived naturally and gave birth at Brussels' Cliniques Universitaires Saint-Luc this week, the Lancet reported.

    Researchers said all young women with cancer should be offered the treatment.

    Our findings open new perspectives for young cancer patients facing premature ovarian failure

    Professor Jacques Donnez, Catholic University of Leuven

    New mother Quarda Touirat, speaking at a press conference on Friday, said: "I'm very happy, it's what I've always wanted. It was a dream."

    Baby Tamara, weighing 3.72kg (just over 8lbs) was born on Thursday night.

    A spokeswoman for the Cliniques Universitaires Saint-Luc said mother and baby were in good health.

    A spokeswoman for the hospital said: "It is the first birth ever of its kind.

    "The implications are that if it has worked once it can be proposed to other women in a similar situation - woman who are suffering from certain kinds of cancer.

    "When they are cured this tissue can be re-implanted and hopefully pregnancy could ensue from that. Obviously the implications for the future are great."

    Lifesaving cancer treatment as a child of young adult can cause many women to go through an early menopause and become infertile. Radiotherapy is thought to be harmful than chemotherapy.

    Experts stress most women who undergo chemotherapy will not become infertile. However the treatment may lead the length of time they are fertile being shortened.

    Doctors across the world have been working to enable cancer patients to become pregnant for many years.

    The Belgian doctors say the fact that a successful birth has been achieved offers hope to thousands of infertile cancer patients.

    The Cliniques Universitaires Saint-Luc says it has frozen ovarian tissue from 146 other cancer patients. So far, the tissue has been reimplanted in two.

    Ethics

    Professor Jacques Donnez, who led the research into the treatment at the Catholic University of Leuven, said: "Our findings open new perspectives for young cancer patients facing premature ovarian failure."


    What they have done is shown that they can make this treatment work.

    Professor Robert Souhami, Cancer Research UK,
    But there are ethical implications over the treatment's potential use to beat the menopause.

    Women are born with a supply of eggs - normally about a million - which die off during their lives until the menopause, when there are too few left to support a pregnancy.

    The technique involves stripping a 1-2mm layer from the ovaries and cutting it into sections, which are then frozen in liquid nitrogen at a temperature of almost -200ºC.

    The tissue can later be transplanted to any part of the body and still function.

    Eggs can then be removed and used in IVF treatment, but in the Belgian case, the tissue was placed at the ends of the fallopian tubes allowing a natural pregnancy.

    Graft

    Ms Touirat had undergone chemotherapy and radiotherapy for Hodgkin's lymphoma.

    Prior to the treatment, some of her ovarian tissue was removed and frozen. One ovary was left inside her body.

    When she was declared cancer-free in April 2003, the ovarian tissue was transplanted back into her body, just below her existing ovary.

    Four months later, she was found to be menstruating and ovulating normally.

    It was revealed that she had become pregnant in June this year.

    In their Lancet paper, the researchers say all the evidence they can see shows that the egg follicle, which ripened into the egg during the menstrual cycle in which Mrs Touirat became pregnant, came from the transplanted tissue.

    Professor Robert Souhami, an executive director of Cancer Research UK, told BBC News Online: "What they have done is shown that they can make this treatment work.

    "Having shown it in one person, they know how to do it in a second.

    "And the more times it is done, the more times you are likely to have a success."

    He said many thousands of women worldwide could benefit.

    But he said: "What we've got to do is define which women are at the highest risk of infertility."

    Simon Davies, Chief Executive of Teenage Cancer Trust says: "This is a fantastic development and offers real hope to females diagnosed with cancer."

  2. #2
    Ardross
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    More cheering news :

    Red Wine Reduces Prostate Cancer Risk - 23-Sep-2004


    Drinking a glass of red wine a day can cut a man's risk of prostate cancer in half, and the protective effect appears to be strongest against the most aggressive forms of the disease, according to a new study led by investigators at the Fred Hutchinson Cancer Research Center.
    The findings, by Janet L. Stanford and colleagues in Fred Hutchinson's Public Health Sciences Division, appear online in The International Journal of Cancer.

    "We found that men who consumed four or more glasses of red wine per week reduced their risk of prostate cancer by 50 percent," Stanford said. "Among men who consumed four or more 4-ounce glasses of red wine per week, we saw about a 60 percent lower incidence of the more aggressive types of prostate cancer," said Stanford, senior author of the study. "The more clinically aggressive prostate cancer is where the strongest reduction in risk was observed."

    Stanford and colleagues believe that is the presence of the antioxdant, Resveratrol, which is abundant in the skins of red grapes but much less so in the skins of white grapes which is the key to their findings. "Even though this study is based on relatively small numbers, the results are very intriguing and suggest that the potential beneficial effect of red wine and resveratrol - if indeed resveratrol is the active chemopreventive agent involved - would be very important, because it's the more aggressive forms of prostate cancer than are most important to prevent," she said.

    Stanford and colleagues plan to seek funding to conduct a larger study to see if their results hold up.

  3. #3
    Senior Member Shadow Leader's Avatar
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    You'll b eok then, James!!!!
    Moderation is a fatal thing. Nothing succeeds like excess.

    False face must hide what the false heart doth know.

  4. #4
    Ardross
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    I am doing my best with forcing this red wine stuff down

  5. #5
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    I know.......difficult task, but someone's got to do it on behalf of those of us who can't drink it.... :cry:
    Moderation is a fatal thing. Nothing succeeds like excess.

    False face must hide what the false heart doth know.

  6. #6
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    A sterling effort, James.

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